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transcriptome analyses console version 4.0  (Thermo Fisher)


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    Structured Review

    Thermo Fisher transcriptome analyses console version 4.0
    Transcriptome Analyses Console Version 4.0, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/transcriptome analyses console version 4.0/product/Thermo Fisher
    Average 90 stars, based on 1 article reviews
    transcriptome analyses console version 4.0 - by Bioz Stars, 2026-06
    90/100 stars

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    Thermo Fisher transcriptome analyses console version 4.0
    Transcriptome Analyses Console Version 4.0, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/transcriptome analyses console version 4.0/product/Thermo Fisher
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    Thermo Fisher transcriptome analyses console
    Differential rhythm analysis reveals changes in liver <t>transcriptome</t> rhythms that affect lipid and cholesterol metabolism in MMI mice. ( A ) Differential rhythm analysis was performed using CircaCompare and is represented as Venn diagrams. ( B ) UpSet plots show alterations in diurnal rhythm parameters (mesor, amplitude, phase). ( C ) Gene set enrichment analysis (GSEA) of the genes with either mesor, amplitude, or phase alterations was performed. Top-5 biological processes for each category are shown. ( D ) In-depth diurnal lipid metabolism analysis in response to low thyroid hormone state. Heatmaps show genes with mesor changes. Volcano plot and rose plot show alterations in amplitude and phase, respectively. ( E ) Normalized gene expression of selected genes participating in cholesterol uptake, biosynthesis, and degradation (bile acid secretion) in CON and MMI mice. ( F ) Quantification of cholesterol and TAG in serum or liver. Presence (R) or absence (NR) of significant circadian rhythm by CircaCompare ( p value < 0.05) is depicted. n = 3–4 for all ZTs and groups.
    Transcriptome Analyses Console, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/transcriptome analyses console/product/Thermo Fisher
    Average 90 stars, based on 1 article reviews
    transcriptome analyses console - by Bioz Stars, 2026-06
    90/100 stars
      Buy from Supplier

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    Thermo Fisher transcriptome analyses console software version 4.0.1
    Differential rhythm analysis reveals changes in liver <t>transcriptome</t> rhythms that affect lipid and cholesterol metabolism in MMI mice. ( A ) Differential rhythm analysis was performed using CircaCompare and is represented as Venn diagrams. ( B ) UpSet plots show alterations in diurnal rhythm parameters (mesor, amplitude, phase). ( C ) Gene set enrichment analysis (GSEA) of the genes with either mesor, amplitude, or phase alterations was performed. Top-5 biological processes for each category are shown. ( D ) In-depth diurnal lipid metabolism analysis in response to low thyroid hormone state. Heatmaps show genes with mesor changes. Volcano plot and rose plot show alterations in amplitude and phase, respectively. ( E ) Normalized gene expression of selected genes participating in cholesterol uptake, biosynthesis, and degradation (bile acid secretion) in CON and MMI mice. ( F ) Quantification of cholesterol and TAG in serum or liver. Presence (R) or absence (NR) of significant circadian rhythm by CircaCompare ( p value < 0.05) is depicted. n = 3–4 for all ZTs and groups.
    Transcriptome Analyses Console Software Version 4.0.1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/transcriptome analyses console software version 4.0.1/product/Thermo Fisher
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    Thermo Fisher transcriptomic analyses console (tac)
    Differential rhythm analysis reveals changes in liver <t>transcriptome</t> rhythms that affect lipid and cholesterol metabolism in MMI mice. ( A ) Differential rhythm analysis was performed using CircaCompare and is represented as Venn diagrams. ( B ) UpSet plots show alterations in diurnal rhythm parameters (mesor, amplitude, phase). ( C ) Gene set enrichment analysis (GSEA) of the genes with either mesor, amplitude, or phase alterations was performed. Top-5 biological processes for each category are shown. ( D ) In-depth diurnal lipid metabolism analysis in response to low thyroid hormone state. Heatmaps show genes with mesor changes. Volcano plot and rose plot show alterations in amplitude and phase, respectively. ( E ) Normalized gene expression of selected genes participating in cholesterol uptake, biosynthesis, and degradation (bile acid secretion) in CON and MMI mice. ( F ) Quantification of cholesterol and TAG in serum or liver. Presence (R) or absence (NR) of significant circadian rhythm by CircaCompare ( p value < 0.05) is depicted. n = 3–4 for all ZTs and groups.
    Transcriptomic Analyses Console (Tac), supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 90 stars, based on 1 article reviews
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    Differential rhythm analysis reveals changes in liver transcriptome rhythms that affect lipid and cholesterol metabolism in MMI mice. ( A ) Differential rhythm analysis was performed using CircaCompare and is represented as Venn diagrams. ( B ) UpSet plots show alterations in diurnal rhythm parameters (mesor, amplitude, phase). ( C ) Gene set enrichment analysis (GSEA) of the genes with either mesor, amplitude, or phase alterations was performed. Top-5 biological processes for each category are shown. ( D ) In-depth diurnal lipid metabolism analysis in response to low thyroid hormone state. Heatmaps show genes with mesor changes. Volcano plot and rose plot show alterations in amplitude and phase, respectively. ( E ) Normalized gene expression of selected genes participating in cholesterol uptake, biosynthesis, and degradation (bile acid secretion) in CON and MMI mice. ( F ) Quantification of cholesterol and TAG in serum or liver. Presence (R) or absence (NR) of significant circadian rhythm by CircaCompare ( p value < 0.05) is depicted. n = 3–4 for all ZTs and groups.

    Journal: Scientific Reports

    Article Title: Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice

    doi: 10.1038/s41598-023-50374-z

    Figure Lengend Snippet: Differential rhythm analysis reveals changes in liver transcriptome rhythms that affect lipid and cholesterol metabolism in MMI mice. ( A ) Differential rhythm analysis was performed using CircaCompare and is represented as Venn diagrams. ( B ) UpSet plots show alterations in diurnal rhythm parameters (mesor, amplitude, phase). ( C ) Gene set enrichment analysis (GSEA) of the genes with either mesor, amplitude, or phase alterations was performed. Top-5 biological processes for each category are shown. ( D ) In-depth diurnal lipid metabolism analysis in response to low thyroid hormone state. Heatmaps show genes with mesor changes. Volcano plot and rose plot show alterations in amplitude and phase, respectively. ( E ) Normalized gene expression of selected genes participating in cholesterol uptake, biosynthesis, and degradation (bile acid secretion) in CON and MMI mice. ( F ) Quantification of cholesterol and TAG in serum or liver. Presence (R) or absence (NR) of significant circadian rhythm by CircaCompare ( p value < 0.05) is depicted. n = 3–4 for all ZTs and groups.

    Article Snippet: Data were analyzed using Transcriptome Analyses Console (Thermo Fisher Scientific, version 4.0) and expressed in log 2 values.

    Techniques: Gene Expression

    Lowering thyroid hormone state has subtle effects on liver transcriptome rhythms. ( A ) Global DEG analysis (disregarding sampling time) is represented as a Venn diagram. ( B ) UpSet plots represent DEG analysis for each ZT separately. ( C ) Venn diagram represents all temporal DEGs (i.e., showing different expression levels of at least one ZT) identified in MMI and T 3 groups versus CON mice. ( D ) Selected examples of robust DEGs (37 in total) previously identified in T 3 -treated mice. Absolute fold change comparison of all 37 DEGs in T 3 and MMI mice are shown. Absolute fold changes were used as some genes were up- or downregulated across the groups. ( E ) Selective TH output genes and fold change of these genes. Comparisons were performed using two-way ANOVA (main treatment effect, p < 0.05). n = 3–4 for all ZTs and groups. Pair-wise comparisons were performed by Student’s t test with Welch correction. Presence (R) or absence (NR) of circadian rhythm by JTK cycle ( p value < 0.05). ***, **** represents a p value of < 0.001, and 0.0001, respectively.

    Journal: Scientific Reports

    Article Title: Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice

    doi: 10.1038/s41598-023-50374-z

    Figure Lengend Snippet: Lowering thyroid hormone state has subtle effects on liver transcriptome rhythms. ( A ) Global DEG analysis (disregarding sampling time) is represented as a Venn diagram. ( B ) UpSet plots represent DEG analysis for each ZT separately. ( C ) Venn diagram represents all temporal DEGs (i.e., showing different expression levels of at least one ZT) identified in MMI and T 3 groups versus CON mice. ( D ) Selected examples of robust DEGs (37 in total) previously identified in T 3 -treated mice. Absolute fold change comparison of all 37 DEGs in T 3 and MMI mice are shown. Absolute fold changes were used as some genes were up- or downregulated across the groups. ( E ) Selective TH output genes and fold change of these genes. Comparisons were performed using two-way ANOVA (main treatment effect, p < 0.05). n = 3–4 for all ZTs and groups. Pair-wise comparisons were performed by Student’s t test with Welch correction. Presence (R) or absence (NR) of circadian rhythm by JTK cycle ( p value < 0.05). ***, **** represents a p value of < 0.001, and 0.0001, respectively.

    Article Snippet: Data were analyzed using Transcriptome Analyses Console (Thermo Fisher Scientific, version 4.0) and expressed in log 2 values.

    Techniques: Sampling, Expressing, Comparison